Revista de ciencias farmacéuticas y medicamentos emergentes

A study of thyroid function cardiac risk assessment profile and hematological changes in HIV infected patients and AIDS patients

Uma Manivannan

The Human Immunodeficiency Virus (HIV) causes acquired immunodeficiency syndrome (AIDS), which a deadly sickness is caused by a retrovirus known as the Human Immunodeficiency Virus (HIV). HIV attacks CD4 cells and leads to AIDS. In India, 2.47 million people are infected with HIV, accounting for 0.36% of the adult population. The updated national estimate reflects improved data rather than a significant reduction in real HIV prevalence in India. The most common mode of transmission is still sexual (87.4%); other modes of transmission, in order of proportion, are prenatal (4.7%), unsafe blood and blood products (1.7%), infected needles and syringes (1.8%), and unspecified (1.7%). (4.1%). Three HIV-positive men were found to have hypercholesterolemia as well as hypertriglyceridemia. In people with AIDS, a link has been discovered between plasma triglyceride and circulating interferon levels. The mechanism of hypercholesterolemia in HIV and other diseases, on the other hand, is unknown. In individuals treated with protease inhibitors, a pattern of hyperlipidaemia has been reported (i.e., higher total cholesterol, low-density lipoprotein cholesterol, and triglycerides, with a decreased level of highdensity lipoprotein cholesterol). Infection can raise plasma triglyceride levels by slowing the clearance of circulating lipoproteins, which is thought to be due to a lack of Lipoprotein Lipase (LPL), or by promoting hepatic lipid synthesis. Increased hepatic fatty acid synthesis or re-esterification of lipolytic fatty acids.