Revista de investigación en dermatología clínica

Metformin as Adjunctive Therapy in Acanthosis Nigricans Treatment: Two Arms Single Blinded Clinical Trial

Alkhayrat A, Alshamrani N, Alshaigi Lama, Alsuwandi Madhawi, Aldayel Atheer, Algodair A, Alghamdi W and Alsuwaidan S* (Saudi Arabia)

Acanthosis nigricans (AN) is a skin disorder that is characterized by?dark?discolorations?with?velvety?texture.?The?safety?and?efficacy? of using metformin as adjunctive therapy to the topical agents in AN remain uncertain. Our primary objective is to quantify AN severity improvement.