Revista de nanomateriales y nanotecnología molecular

Platinum and Copper Supported in Functionalized Titania Nanoparticles for the Treatment of Cervical and Prostate Cancer

Lopez T, Larraza P and Gomez E

Today, cancer is one of the main causes of mortality. The most common treatments are chemotherapy, surgery, radiology and radiosurgery. The catalytic nanomedicine is a new research branch focused on the preparation of nanobiomaterials with medical applications to create a targeted therapy. The goal of this study was to determine the cytotoxic effect of the platinum nanoparticle (NPt) and the copper nanoparticle (NP-Cu) in lines of cancer cells as well as healthy cells for the cervical uterus cancer (HeLa), prostate cancer (DU 145). The catalyst nanoparticles used to break the bonds C-C, C-N and C=O in nitrogenous bases were synthesized in a sol-gel process. It is proven that they were biocompatible and non-toxic. Cell barriers were crossed with platinum and copper supported on functionalized titania (TiO2). In vitro tests were performed giving as a result that the NPt nanoparticles are much slower than the NP-Cu ones.