Johannes Wogatzky, Dietmar Spitzer, Maximilian Schuff, Birgit Schechinger and Nicolas H. Zech
Antioxidant Supplementation of Subfertile Men Improves Top-Blastocyst Rate in Couples Undergoing IVF/IMSI
In recent years, oxidative stress (OS) has been identified as important factor in male infertility. Thus, the intake of antioxidants to improve semen quality (in subfertile men) has been widely discussed. Improvements of semen quality after supplementation have been reported. However, this issue is still underevaluated. Critics complain a lack of data regarding firstly the use of antioxidants due to the heterogeneity between patient groups, nutritional supplements and treatment effect and secondly rare data in regard to the impact of supplementation on assisted reproduction technique (ART) outcome. In this study the effect of an antioxidant supplementation (AOS) on semen quality and therapy outcome of 92 couples undergoing fertility treatment was assessed..
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