Investigación en endocrinología y diabetes

Redox-Active Biofactors and their Possible Metabolic Relevance

Amandio Vieira

Redox-Active Biofactors and their Possible Metabolic Relevance

Excess levels of redox-active iron in the body contribute to a wide range of diseases, including major chronic diseases that afflict developed countries, e.g., some types of cancer, type 2 diabetes, and major cardiovascular diseases. The role of iron in these different pathologies is complex. Forms of hereditary haemochromatosis are examples of iron-excess conditions, but other such conditions are also widespread; and they can differ greatly in the severity of iron-overload